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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C12orf48
All Species:
19.09
Human Site:
S540
Identified Species:
42
UniProt:
Q9NWS1
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NWS1
NP_060385.2
579
65081
S540
N
A
K
I
P
K
K
S
N
D
S
Q
N
R
L
Chimpanzee
Pan troglodytes
XP_509318
760
85084
S721
N
A
K
I
P
K
K
S
N
D
S
Q
N
R
L
Rhesus Macaque
Macaca mulatta
XP_001085518
579
65125
S540
N
V
K
I
P
K
K
S
N
D
S
Q
N
K
L
Dog
Lupus familis
XP_855025
579
65071
S540
N
V
K
I
P
K
T
S
N
N
F
Q
N
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6IRT3
573
64087
P534
N
I
K
I
P
K
V
P
S
G
S
H
S
K
A
Rat
Rattus norvegicus
Q9EQ10
573
63884
P534
N
V
K
I
L
K
V
P
S
D
S
H
R
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507285
579
64417
S540
V
V
K
R
S
K
T
S
S
N
P
L
D
K
L
Chicken
Gallus gallus
Q5ZKL9
580
65236
S541
N
A
K
K
L
K
T
S
N
N
P
Q
K
E
L
Frog
Xenopus laevis
Q32N66
567
63030
K528
Q
E
N
E
P
P
Q
K
K
A
V
V
E
L
T
Zebra Danio
Brachydanio rerio
Q1RMA6
568
62451
P529
Q
G
R
E
E
N
Q
P
P
Q
K
R
P
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001178396
861
96268
T742
F
A
M
L
P
G
S
T
V
T
V
A
S
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.7
94.4
82.3
N.A.
69.2
68.7
N.A.
63.2
54.4
50
39.3
N.A.
N.A.
N.A.
N.A.
20.4
Protein Similarity:
100
75.5
96.7
90.6
N.A.
81.3
80.6
N.A.
78.4
72
64.5
56.6
N.A.
N.A.
N.A.
N.A.
37.5
P-Site Identity:
100
100
86.6
66.6
N.A.
40
40
N.A.
26.6
53.3
6.6
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
93.3
80
N.A.
60
53.3
N.A.
53.3
60
13.3
20
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
37
0
0
0
0
0
0
0
10
0
10
0
0
28
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
37
0
0
10
0
0
% D
% Glu:
0
10
0
19
10
0
0
0
0
0
0
0
10
10
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
10
0
0
0
10
0
0
0
10
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% H
% Ile:
0
10
0
55
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
73
10
0
73
28
10
10
0
10
0
10
46
0
% K
% Leu:
0
0
0
10
19
0
0
0
0
0
0
10
0
10
55
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
64
0
10
0
0
10
0
0
46
28
0
0
37
0
0
% N
% Pro:
0
0
0
0
64
10
0
28
10
0
19
0
10
10
0
% P
% Gln:
19
0
0
0
0
0
19
0
0
10
0
46
0
0
0
% Q
% Arg:
0
0
10
10
0
0
0
0
0
0
0
10
10
19
0
% R
% Ser:
0
0
0
0
10
0
10
55
28
0
46
0
19
0
10
% S
% Thr:
0
0
0
0
0
0
28
10
0
10
0
0
0
0
10
% T
% Val:
10
37
0
0
0
0
19
0
10
0
19
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _